Our lab uses theoretical and computational techniques to study a wide variety of soft condensed matter systems both in and out of equilibrium. How do we explain the way disordered solids maintain their rigidity, and also how they fail? What can simple models of active matter teach us about the collective behavior of cells in dense tissue, or about how birds flock? We focus on the role of topology and topological interactions in protecting system behaviors even in the presence of strong fluctuations – this allows us to make strong predictions about how a system responds to perturbations even when using extremely simplified, coarse-grained representations. We employ data-science-driven techniques, working closely with experiments, to formulate precisely tests that can discriminate between different theoretical approaches. And we ask how novel broken symmetries in coarse-grained descriptions of living matter leads to new phase transitions in models of soft living active matter.
See below for a rolling list of recent group news!
Another paper at the intersection of experimental work and numerical modeling. Working with the Gardel lab, we find that cell shape is controlled by rigidity and active stresses within the tissue, and show that cell cycle dynamics are the source of active stress that drives epithelial remodeling. Read the work in Proceedings of the National Academy of Sciences.
Together with an experimental team in Leipzig, we talk about connections between single-cell information and tissue-scale material properties in 3D cell cultures. Work published in Physical Review X!
Models of dense biological tissue? Glassy behavior? Machine learning? Check out this collaboration with Tristan Sharp, Indrajit Tah, and Andrea Liu in Soft Matter!
Our first undergraduate researcher, Sumedh, has joined the group – welcome! Sumedh is a sophomore working with the SIRE program to his first look at what research is like. Looking forward to working together this year and, hopefully, beyond!
We’re thrilled to welcome the group’s first postdoctoral scholar, and one of Emory’s TMLS postdoctoral fellows, Dr. Haicen Yue! Haicen’s Ph.D. was completed in the Rappel lab at UC San Diego, and she’s joining us after being a postdoc at the Courant Institute working with Alex Mogilner. The whole group is excited to have the chance to work with Haicen over the next few years!
Daniel’s first Emory-based single-author-paper has been published! Check out the open-access article, and head over to the GitHub page if you want to run your own simulations of cellular models in curved space!
A joint paper with Daniel Beller’s group has been published! Check out the paper for details, and our open-source software package for running your own simulations.
We’re starting our group, studying many different flavors of theoretical and computational soft matter, at Emory University! Excited to hit the ground, start recruiting students, and all that. Surely there’s not going to be a global pandemic just around the corner which would make starting this year tough, right?
